P0300 OBD2 Code After Installing Spark Plugs and Wires on 2007 Chevrolet Silverado LT 5.3L

Model: 2007 Silverado LT 5.3L Fault Code: P0300 Posted: 2012-03-12 16:44

My 2007 Chevrolet Silverado LT with a 5.3L engine is running roughly, and the engine check light is illuminated steadily. I recently replaced the spark plugs and ignition wires, but the P0300 random misfire code has persisted. Any suggestions on how to troubleshoot or resolve this issue? The vehicle was previously running smoothly before the replacement.