2005 Dodge Stratus SXT P0300 Code: Misfire Diagnosis and Solutions

Hi everyone! I'm currently dealing with a 2005 Dodge Stratus SXT (2.7L 6-cylinder) that consistently shows the P0300 diagnostic trouble code, indicating a random misfire. Despite replacing the throttle position sensor, spark plugs, and air filter—none of these fixes have resolved the issue. The vehicle stalls intermittently, especially when driving in gear. It runs smoothly at idle but begins to cut out after just a few blocks of driving, with the problem worsening over time. When shifted back into park, it returns to normal idling behavior. I've already added fuel treatment to address potential water contamination in the fuel system. We also inspected and resecured all air filter connections to eliminate possible leaks. After these steps, we reset both the engine control module (ECM) manually and using a diagnostic scanner. Has anyone else experienced similar P0300 issues with this model? What specific symptoms or diagnostics would help pinpoint whether it's a fuel delivery, ignition, or mechanical issue? The ongoing trial-and-error process is becoming increasingly costly. Any insights, suggestions, or known common causes for this code in the 2005 Dodge Stratus SXT would be greatly appreciated. Thanks in advance!