2002 Chevy Blazer P0300 Multiple Misfires: Diagnosis and Exhaust Back Pressure Solution
I own a 2002 Chevrolet Blazer that is experiencing severe performance issues. The vehicle runs very poorly, stalling at around 1.5K RPM and failing to move down the road. It consistently displays fault code P0300 (multiple misfires). However, when I remove the front driver's side oxygen sensor, the engine runs smoothly with no misfire symptoms and the P0300 code disappears. I have already inspected and replaced key components including the MAF sensor, fuel filter, PCV valve, and exhaust system. A new oxygen sensor has been installed, but the issue persists—both old and new sensors result in identical performance problems. I also checked for catalytic converter blockage by poking a hole through it using a long iron rod from the front to the back (via an existing union), and even rerouted the exhaust pipe around the converter with the union open. Despite these efforts, the vehicle still bogs down under load. After resetting the ECU with the oxygen sensor removed, only P0453 (exhaust system leak or pressure issue) remains—a code I've had for some time. All other oxygen sensors appear to function normally and do not affect engine performance. I am now concerned whether this is a backpressure-related problem or another underlying cause. Any insights or suggestions would be greatly appreciated.
The fact that the vehicle runs normally when the front driver's side oxygen sensor is removed strongly suggests a restriction in the exhaust system downstream of that sensor.